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Andrew F G Quest Selected Research

Caveolin 1

6/2022Mitochondrial Dysfunction and the Glycolytic Switch Induced by Caveolin-1 Phosphorylation Promote Cancer Cell Migration, Invasion, and Metastasis.
8/2020Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in Hypoxia.
1/2020Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response.
1/2020The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis.
1/2020Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells.
9/2019AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells.
12/2017Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells.
1/2017Caveolin-1 Expression Increases upon Maturation in Dendritic Cells and Promotes Their Migration to Lymph Nodes Thereby Favoring the Induction of CD8+ T Cell Responses.
6/2016Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis.
6/2015Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells.
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Andrew F G Quest Research Topics

Disease

44Neoplasms (Cancer)
06/2022 - 01/2002
19Melanoma (Melanoma, Malignant)
06/2022 - 11/2007
18Neoplasm Metastasis (Metastasis)
06/2022 - 11/2007
9Breast Neoplasms (Breast Cancer)
01/2020 - 04/2009
7Inflammation (Inflammations)
01/2022 - 03/2012
7Hypoxia (Hypoxemia)
01/2022 - 01/2014
5Colonic Neoplasms (Colon Cancer)
12/2017 - 11/2007
5Necrosis
08/2013 - 12/2002
4Infections
01/2018 - 10/2010
3Ovarian Epithelial Carcinoma
10/2020 - 01/2018
2Stomach Neoplasms (Stomach Cancer)
06/2019 - 02/2018
2Adenocarcinoma
06/2019 - 06/2015
2Lymphoma (Lymphomas)
03/2008 - 12/2002
2Carcinoma (Carcinomatosis)
01/2002 - 01/2002
1Mitochondrial Diseases (Mitochondrial Disease)
06/2022
1Autoimmune Diseases (Autoimmune Disease)
01/2022
1Residual Neoplasm
01/2022
1Disease Progression
01/2021
1Juvenile Amyotrophic Lateral Sclerosis 2
12/2020
1Weight Gain
07/2020
1Glucose Intolerance
07/2020
1Type 2 Diabetes Mellitus (MODY)
07/2020
1Cicatrix (Scar)
01/2020
1Rupture
01/2018
1Ovarian Neoplasms (Ovarian Cancer)
01/2018
1Neuroinflammatory Diseases
09/2017
1Carcinogenesis
06/2016

Drug/Important Bio-Agent (IBA)

24Proteins (Proteins, Gene)FDA Link
06/2022 - 01/2002
21Caveolin 1IBA
06/2022 - 01/2002
10SurvivinIBA
11/2020 - 05/2006
7IntegrinsIBA
01/2020 - 05/2016
4Messenger RNA (mRNA)IBA
12/2020 - 11/2007
4CateninsIBA
10/2020 - 01/2011
4Cadherins (E-Cadherin)IBA
08/2020 - 11/2007
4Small Interfering RNA (siRNA)IBA
05/2016 - 01/2012
3Nerve Growth Factor (NGF)IBA
10/2020 - 01/2018
3Virulence Factors (Pathogenicity Factors)IBA
06/2019 - 01/2018
3Inhibitor of Apoptosis ProteinsIBA
01/2014 - 05/2006
3AntigensIBA
01/2014 - 01/2010
3CaspasesIBA
07/2011 - 12/2002
2Phosphotransferases (Kinase)IBA
01/2021 - 01/2020
2Pharmaceutical PreparationsIBA
10/2020 - 12/2017
2Metformin (Glucophage)FDA LinkGeneric
10/2020 - 01/2018
2Biological ProductsIBA
01/2020 - 10/2009
2Adenosine Triphosphate (ATP)IBA
01/2020 - 03/2008
2src-Family KinasesIBA
01/2020 - 12/2017
2Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2020 - 09/2019
2Dinoprostone (PGE2)FDA Link
12/2019 - 11/2011
2Tyrosine (L-Tyrosine)FDA Link
09/2019 - 06/2016
2CytokinesIBA
09/2017 - 03/2012
2MucinsIBA
08/2015 - 03/2012
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
11/2011 - 04/2009
2CeramidesIBA
03/2008 - 12/2002
1Deoxyglucose (2 Deoxy D glucose)IBA
06/2022
1MicroRNAs (MicroRNA)IBA
01/2022
1HhAntag691IBA
08/2021
1GTP Phosphohydrolases (GTPases)IBA
12/2020
1Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA
12/2020
1ChromatinIBA
12/2020
1Apoptosis Regulatory ProteinsIBA
11/2020
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2020
1arginine methyl esterIBA
08/2020
1Nitric Oxide Synthase (NO Synthase)IBA
08/2020
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
08/2020
1Nonesterified Fatty Acids (NEFA)IBA
07/2020
1Insulin (Novolin)FDA Link
07/2020
1CholesterolIBA
07/2020
1GoldIBA
01/2020
1Dasatinib (BMS 354825)FDA Link
01/2020
1Glycoproteins (Glycoprotein)IBA
01/2020
1Cell Adhesion MoleculesIBA
01/2020
1SyndecansIBA
01/2020
1Mutant Proteins (Protein, Mutant)IBA
01/2020
1tyrosine receptor (receptor, tyrosine)IBA
01/2020
1Purinergic P2X7 ReceptorsIBA
01/2020
1Syndecan-4IBA
01/2020
1Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA
09/2019
1Angiotensin Receptors (Angiotensin II Receptor)IBA
09/2019
1ReninIBA
09/2019
1rac1 GTP-Binding ProteinIBA
09/2019
1Factor Xa (Coagulation Factor Xa)IBA
08/2019
1Dalteparin (Dalteparin Sodium)FDA Link
08/2019
1AnticoagulantsIBA
08/2019
1UreaseIBA
06/2019
1Blocking AntibodiesIBA
06/2019
1CurcuminIBA
12/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2018
15-hydroxymethylcytosineIBA
11/2018
1ParaffinIBA
02/2018
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2018
1MethyltransferasesIBA
12/2017
1Cyclin D1IBA
01/2017
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
01/2017
1Transcription Factors (Transcription Factor)IBA
01/2017
1Monomeric GTP-Binding ProteinsIBA
05/2016
1LactonesIBA
03/2016

Therapy/Procedure

4Therapeutics
01/2022 - 01/2014
4Drug Therapy (Chemotherapy)
01/2022 - 01/2014
4Subcutaneous Injections
12/2018 - 04/2014
1Precision Medicine
07/2021